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Symbol
Name
ID

Chn1
chimerin 1
MGI:1915674

Phenotype annotations related to nervous system

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Microcephaly	Blepharospasm	Oculomotor apraxia	Oculomotor nerve palsy	Gustatory lacrimation	Spina bifida occulta	Global developmental delay	Seizure
Disease(s) Associated with CHN1
Duane retraction syndrome

Mouse Phenotypes

nervous system phenotype

tonic seizures

abnormal axon extension

abnormal axon fasciculation

enlarged brain ventricles

abnormal cerebral cortex morphology

abnormal innervation

abnormal motor neuron innervation pattern

abnormal corticospinal tract morphology

decreased motor neuron number

abnormal spinal cord interneuron morphology

abnormal abducens nerve morphology

abnormal spinal nerve morphology

abnormal spinal cord morphology

abnormal spinal cord dorsal column morphology

abnormal central pattern generator function

abnormal nervous system electrophysiology

abnormal nerve fiber response

Availability

Mouse Genotype

Chn1^Gt714Lex/Chn1^Gt714Lex

*

Chn1^mfy/Chn1^mfy

Chn1^tm1.1Abet/Chn1^tm1.1Abet

Chn1^tm1.1Ece/Chn1^tm1.1Ece
Tg(Hlxb9-GFP)1Tmj/0

Chn1^tm1.1Ece/Chn1^tm1.1Ece
Tg(Isl1-EGFP*)1Slp/0

Chn1^tm1.1Ito/Chn1^tm1.1Ito

Chn1^tm1.2Ece/Chn1^tm1.2Ece
Tg(Hlxb9-GFP)1Tmj/0

Chn1^tm2Abet/Chn1^tm2Abet

Chn1^tm1.1Ece/Chn1⁺
Tg(Hlxb9-GFP)1Tmj/0

Chn1^tm1Ito/Chn1^tm1.1Ito
Tg(Slc17a6-icre)1Oki/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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